Pioneering discoveries: Our science
62M
PATIENTS
Most common
joint disease
$140B
ESTIMATED COSTS
Increasing annual
medical costs
RISE
DISABILITY
Leading cause
of disability
In the past, OA was classified as a form of arthritis that resulted from mechanical wear and tear. However, current biochemical analysis suggests that it is actually a chronic inflammatory disease.
Currently, there are no pharmaceutical solutions that effectively treat OA, despite the high demand. Pain-controlling medications are associated with significant side effects, and joint replacement – the last resort treatment – is invasive and poses surgical risks with mixed clinical outcomes.
“Presently, there are no drugs that can prevent, stop or even restrain progression of OA.”
Osteoarthritis Research Society International (OARSI)
A well-defined pattern of inflammatory cascade is seen in OA, mediated through changes in redox potential. Clinically, once OA has set in, inflammatory mediators are present, cell death occurs, the cartilaginous layer progressively thins, and the health and biomechanics of the joint irreversibly degrade.
At Snow Canyon, we are working to change this.
Snow Canyon Therapeutics focuses on reversing this process, stopping the inflammatory cascade that causes the joint to become arthritic and allowing the cartilage to heal.
By safely regulating oxidation, we can bring desperately needed relief to millions of people suffering from chronic inflammation.
Redox homeostasis is the prime target in chronic inflammatory treatment.
Areas of Focus
Our mission is to develop a range of drug candidates that can significantly impact millions of patients’ lives. Our initial focus is on osteoarthritis, and we use specialized molecules to address the biochemical processes involved directly.
These same molecules can also target other chronic inflammatory diseases linked to oxidative stress dysregulation, including Alzheimer’s disease, type II diabetes, cardiovascular disease, psoriasis and traumatic brain injury.
Linked to oxidative stress
Osteoarthritis
Type II Diabetes
Cardiovascular Disease
Psoriasis
Alzheimer’s Disease
Traumatic Brain Injury
